People with low immunity are susceptible to cancer: the occurrence, development, recurrence rate and survival period of tumors are closely related to the immune status of the body. The human immune system is composed of immune organs, immune cells, immune molecules, and lymphatic circulation network. Immune cells circulate through the blood

Through the quantitative analysis of the changes in the proportion of T lymphocyte subsets in human peripheral blood, the qualitative and quantitative analysis of the diversity of T cell antigen receptors (T CELL RECEPTOR, TCR) to determine the cellular immune response capacity of human individuals (including anti-tumor Ability and anti-infection ability) to guide the determination of clinical anti-tumor treatment plan. Organs and tissues throughout the body.

What is T cell receptor

"The receptor that specifically recognizes the antigen on the surface of mature T cells is called the T cell antigen receptor (TCR), which is also a characteristic surface marker of all T cells." 95% of TCRs are heterodimers composed of α and β chains. Human TCRβ chain genes are more complicated, and gene rearrangements occur in the process of antigen recognition, which play an important role.

TCRβ gene complex includes at least 67 V (variable) gene regions, 2 D (diversity) gene regions, 13 J (joining) gene regions and 2 C (constant) gene regions.